What ingredients do I need to make Bubble Up Biscuit Pizza Casserole?

To make Bubble Up Biscuit Pizza Casserole, you’ll need refrigerated buttermilk biscuits, pizza sauce, shredded mozzarella cheese, and your choice of pizza toppings like pepperoni, Italian sausage, mushrooms, or bell peppers. Optional additions include Italian seasoning, parmesan cheese, and fresh herbs to boost flavor. These simple ingredients combine for a quick, family-friendly meal.

How do I prepare and arrange the biscuits for the pizza casserole?

Start by opening the canned biscuits and cutting each biscuit into quarters or small bite-sized pieces. Spread these evenly in a greased baking dish to create a base layer. This helps the biscuits cook uniformly and absorb the pizza sauce and toppings for a soft, fluffy texture inside the casserole.

What’s the best baking temperature and time for Bubble Up Biscuit Pizza Casserole?

Bake the casserole uncovered at 350°F (175°C) for 25-30 minutes. Cooking at this temperature allows the biscuit dough to bake fully while the cheese melts and turns golden brown. Check that the biscuits in the center are cooked through before removing it from the oven.

Can I customize the toppings for different taste preferences or dietary needs?

Yes, you can easily customize the toppings to suit picky eaters or dietary restrictions. Try dividing the casserole so one half has pepperoni and vegetables, while the other remains vegetarian with olives and bell peppers. For leafy greens like spinach or basil, add them under the cheese or mix into the sauce to prevent burning.

How should I store and reheat leftover Bubble Up Biscuit Pizza Casserole?

Store any leftovers in an airtight container in the refrigerator for up to three days. To reheat, use an air fryer or conventional oven to keep the casserole crispy without drying it out. Reheating in the microwave may result in a soggy texture, so oven reheating is preferred for best results.

Bubble Up Biscuit Pizza Casserole Recipe With Cheesy Layers

Name: Bubble Up Biscuit Pizza Casserole
Prep time: 10 min
Cook time: 30 min
Total time: 40 min
Cuisine: American
Ingredients: 2 cans of refrigerated buttermilk biscuits; 1 jar (15 ounces) of pizza sauce; 2 cups of shredded mozzarella cheese; Pizza toppings such as pepperoni, Italian sausage, mushrooms, olives, bell peppers, onions, and fresh herbs; Parmesan cheese for extra savoriness; Italian seasoning; Red pepper flakes for heat; Plant-based biscuits; Vegan cheese; Tofu or plant-based meats; Gluten-free biscuits; Certified sauce and toppings; Low-fat cheese; Extra veggies

Ingredients

Scale

2 cans of refrigerated buttermilk biscuits

1 jar (15 ounces) of pizza sauce

2 cups of shredded mozzarella cheese

Pizza toppings such as pepperoni, Italian sausage, mushrooms, olives, bell peppers, onions, and fresh herbs

Parmesan cheese for extra savoriness

Italian seasoning

Red pepper flakes for heat

Plant-based biscuits

Vegan cheese

Tofu or plant-based meats

Gluten-free biscuits

Certified sauce and toppings

Low-fat cheese

Extra veggies

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Instructions

1-Preheat the oven to 350°F (175°C): Grease a 9×13-inch baking dish.

2-Open the 2 cans of refrigerated buttermilk biscuits: Cut biscuits into quarters or bite-sized pieces.

3-Arrange the biscuit pieces evenly in a single layer in the dish: Stack slightly near edges if needed.

4-Spread the 15-ounce jar of pizza sauce evenly over the dough.

5-Sprinkle 2 cups of shredded mozzarella cheese over the sauce: Add parmesan if you have it.

6-Add pizza toppings like pepperoni, Italian sausage, mushrooms, olives, bell peppers, onions, and fresh herbs evenly on top.

7-Bake uncovered for 25 to 30 minutes. Dough cooks through, cheese browns. Check center for doneness.

8-Let cool at least 5 minutes before serving.

Notes

🍴 Use one biscuit can for smaller servings or a saucier casserole.
🔪 Cut dough into smaller pieces to ensure faster, even cooking.
⏲️ Precook biscuit dough 5-10 minutes before adding toppings to prevent undercooked centers.

Author: Brandi Oshea
Prep Time: 10 minutes
Cook Time: 30 minutes
Category: Main Course
Method: Baking
Cuisine: American

Nutrition

Serving Size: 1 serving